Nifedipine 20 mg Tablet
Nifedipine 20 mg Tablet
Therapeutic Class: Cardiovascular Agents
Dosage Forms: Tablets
Brand Name: Nifedipine 20 mg Tablet™
How it works?
Uses of Nifedipine 20 mg Tablet
- Hypertension → Relaxes blood vessels, reduces peripheral resistance, and lowers blood pressure. Helps prevent complications such as stroke, heart attack, and kidney damage.
- Chronic stable angina → Improves oxygen supply to the heart, relieves chest pain, and reduces frequency of angina attacks.
- Vasospastic (Prinzmetal’s) angina → Effective in relieving chest pain caused by coronary artery spasms.
- Raynaud’s phenomenon → Sometimes prescribed to improve blood flow in patients with cold‑induced vascular spasms.
- Peripheral vascular disease → Enhances circulation by dilating blood vessels, reducing vascular resistance.
Precautions of Nifedipine 20 mg Tablet
Important Precautions for Nifedipine Tablets 20 mg
Not a Beta-Blocker
- Nifedipine is not a beta-blocker.
- If you’re stopping a beta-blocker, don’t stop suddenly. Reduce the dose slowly over 8–10 days to avoid serious side effects.
- Nifedipine won’t protect you from problems caused by stopping other blood pressure medicines suddenly.
Taking with Other Medicines
- You can take nifedipine with other blood pressure medicines, including beta-blockers.
- But be careful: combining them may cause dizziness or fainting when standing up (called postural hypotension).
- Nifedipine won’t stop the “rebound” effect (rise in blood pressure) that can happen after stopping other medicines.
Heart & Blood Pressure Risks
Use nifedipine carefully if you have:
- Very low blood pressure (systolic pressure below 90 mmHg)
- Heart failure
- Severe narrowing of heart valves (aortic stenosis)
- Weak heart function (poor cardiac reserve)
Sometimes, nifedipine can make heart failure worse.
Pregnancy & Breastfeeding
- Pregnancy: Only use nifedipine if absolutely needed, such as in severe high blood pressure that doesn’t respond to other treatments.
- Breastfeeding: Not recommended. Nifedipine can pass into breast milk, and its effects on babies are unknown.
- If used with IV magnesium sulfate during pregnancy, blood pressure may drop too much—this can harm both mother and baby. Close monitoring is needed.
Diabetes
- If you have diabetes, nifedipine may affect your blood sugar control. Your doctor may need to adjust your treatment.
Liver & Kidney Health
- If you have liver problems, your doctor may lower your dose and monitor you closely.
- In dialysis patients with high blood pressure and low fluid levels, nifedipine may cause a sharp drop in blood pressure.
Drug Interactions
Some medicines can increase the amount of nifedipine in your body. This may cause your blood pressure to drop too much. Tell your doctor if you take:
| Type of Medicine | Examples |
| Antibiotics | Erythromycin |
| Antifungals | Ketoconazole |
| HIV Medicines | Ritonavir |
| Antidepressants | Fluoxetine, Nefazodone |
| Others | Valproic acid, cimetidine, and Quinupristin/Dalfopristin |
Your doctor may need to adjust your dose or monitor your blood pressure more closely.
Lactose Warning
- Nifedipine contains lactose.
- Do not take it if you have:
- Galactose intolerance.
- Lapp lactase deficiency.
- Glucose-galactose malabsorption.
Dosages administration of Nifedipine 20 mg Tablet
Standard Dosage of Nifedipine 20 mg Tablet
- Starting dose: 10 mg every 12 hours
- Titration: Adjust based on patient response
- Typical maintenance dose: 40 mg every 12 hours
- Maximum daily dose: 80 mg
Tablets should be swallowed whole with water. Do not chew or crush.
Duration of Treatment
- Indefinite: Long-term use is acceptable if well tolerated and effective.
| Group | Dosage Adjustment Needed? | Notes |
| Elderly (>65 yrs) | Not required | Pharmacokinetics remain stable |
| Renal impairment | Not required | No dose change necessary |
Side effects of Nifedipine 20 mg Tablet
What are the most common side effects of nifedipine?
Side effects are grouped by how often they happen:
- Common: Affects 1 to 10 out of every 100 people
- Uncommon: Affects 1 to 10 out of every 1,000 people
- Rare: Affects 1 to 10 out of every 10,000 people
- Not Known: Reported after release, but frequency is unclear
Nervous System
- Common: Headache
- Uncommon: Dizziness, vertigo, migraine, tremors
- Rare: Tingling or numbness
- Not Known: Sleepiness, reduced sensation
Heart & Blood Vessels
- Common: Swelling (especially in legs), widened blood vessels
- Uncommon: Low blood pressure, fainting, fast heartbeat, palpitations
- Not Known: Chest pain (angina)
Blood & Immune System
- Uncommon: Allergic reactions, swelling in throat or face
- Rare: Itchy skin, rash, hives
- Not Known: Serious allergic reactions (anaphylaxis), low white blood cells, high blood sugar
Mental Health
- Uncommon: Anxiety, trouble sleeping.
- Not Known: Depression.
Eyes
- Uncommon: Blurred or altered vision.
- Not Known: Eye pain.
Muscles & Joints
- Uncommon: Joint swelling, muscle cramps
- Not Known: Nosebleeds, nasal congestion
Digestive System
- Common: Constipation.
- Uncommon: Stomach pain, nausea, indigestion, gas, dry mouth.
- Rare: Gum overgrowth.
- Not Known: Difficulty swallowing, vomiting, intestinal blockage, or ulcers.
Liver
- Uncommon: Temporary rise in liver enzymes.
Skin
- Uncommon: Redness.
- Rare: Rash, itching, hives.
- Not Known: Severe skin reactions, allergic sun sensitivity, purple spots.
Kidneys & Urinary
- Uncommon: Frequent urination, painful urination.
Reproductive System
- Uncommon: Erectile dysfunction.
General Symptoms
- Common: Feeling unwell.
- Uncommon: General pain, chills.
Special Warnings
- Throat swelling can be life-threatening.
- Pregnancy use (as a tocolytic) has reported serious cases.
- Dialysis patients with low fluid levels may experience a sharp drop in blood pressure.
Storage instruction of Nifedipine 20 mg Tablet
Store below 30°C.
Keep out of reach of children.
Packing details of Nifedipine 20 mg Tablet
3×10 Alu/PVC Blister
Nifedipine 20 mg Tablet is available in an Alu/PVC blister of 10 tablets. Such 3 blisters in a unit carton with package insert.
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Reliable GMP Certified Nifedipine 20 mg Tablet Manufacturer
Conical Pharmaceuticals, headquartered in Ahmedabad, India, is a GMP‑certified manufacturer & exporter of Nifedipine 20 mg Tablets located in Ahmedabad, delivering premium pharmaceutical and nutraceutical solutions worldwide. Also, we are a top supplier across 20+ Countries. Belonging to the calcium channel blocker therapeutic class, Nifedipine is primarily indicated for the treatment of essential hypertension and chronic stable angina. By relaxing blood vessels and reducing peripheral resistance, it lowers blood pressure, improves oxygen supply to the heart, and helps prevent complications such as stroke, heart attack, and kidney damage.
With exports planned into Central Africa, Central America, and the CIS Region, and expanding into Nigeria, Ghana, Zambia, Zimbabwe, Kenya, the Philippines, Singapore, and Afghanistan, Conical Pharmaceuticals ensures reliable supply and smooth market entry. Importers benefit from complete regulatory dossier support, including GMP Certification, COPP, COA, and Free Sale Certificates.
We also provide third‑party contract manufacturing, bulk supply of pharmaceutical tablets, private labelling, and custom formulation options, empowering partners to launch their own brands with tailored solutions. With advanced R&D, flexible MOQ options, and consistent quality assurance, Conical Pharmaceuticals enables partners to expand their market presence while delivering effective, high‑quality cardiovascular therapies worldwide.
CUSTOM PACKAGING
Options available in size and style to meet your exact specifications and branding needs
SAMPLES AVAILABLE
Test before committing to bulk orders with complimentary samples for quality verification
LEAD TIME
45–60 days for timely delivery, ensuring reliable supply chain management
SHELF LIFE
Shelf Life: 24 months.
Frequently Asked Questions
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Conical Pharmaceuticals, headquartered in Ahmedabad, India, is a GMP‑certified manufacturer & exporter of Nifedipine formulations.
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