Nifedipine 20 mg Tablet

Therapeutic Class: Cardiovascular Agents

Dosage Forms: Tablets

Brand Name: Nifedipine 20 mg Tablet

How it works?

Uses of Nifedipine 20 mg Tablet

Nifedipine is primarily used to treat several cardiovascular and vascular conditions due to its potent calcium channel blocking properties. In hypertension, it works by relaxing blood vessels and reducing peripheral resistance, which helps lower blood pressure and prevent complications such as stroke, heart attack, and kidney damage.

Dosages administration of Nifedipine 20 mg Tablet

Standard Dosage of Nifedipine 20 mg Tablet

Starting dose: 10 mg every 12 hours
Titration: Adjust based on patient response
Typical maintenance dose: 40 mg every 12 hours
Maximum daily dose: 80 mg

Tablets should be swallowed whole with water. Do not chew or crush.

Duration of Treatment

Indefinite: Long-term use is acceptable if well tolerated and effective.

Group	Dosage Adjustment Needed?	Notes
Elderly (>65 yrs)	Not required	Pharmacokinetics remain stable
Renal impairment	Not required	No dose change necessary

Side effects of Nifedipine 20 mg Tablet

What are the most common side effects of nifedipine?

Side effects are grouped by how often they happen:

Common: Affects 1 to 10 out of every 100 people
Uncommon: Affects 1 to 10 out of every 1,000 people
Rare: Affects 1 to 10 out of every 10,000 people
Not Known: Reported after release, but frequency is unclear

Nervous System

Common: Headache
Uncommon: Dizziness, vertigo, migraine, tremors
Rare: Tingling or numbness
Not Known: Sleepiness, reduced sensation

Heart & Blood Vessels

Common: Swelling (especially in legs), widened blood vessels
Uncommon: Low blood pressure, fainting, fast heartbeat, palpitations
Not Known: Chest pain (angina)

Blood & Immune System

Uncommon: Allergic reactions, swelling in throat or face
Rare: Itchy skin, rash, hives
Not Known: Serious allergic reactions (anaphylaxis), low white blood cells, high blood sugar

Mental Health

Uncommon: Anxiety, trouble sleeping.
Not Known: Depression.

Eyes

Uncommon: Blurred or altered vision.
Not Known: Eye pain.

Muscles & Joints

Uncommon: Joint swelling, muscle cramps
Not Known: Nosebleeds, nasal congestion

Digestive System

Common: Constipation.
Uncommon: Stomach pain, nausea, indigestion, gas, dry mouth.
Rare: Gum overgrowth.
Not Known: Difficulty swallowing, vomiting, intestinal blockage, or ulcers.

Liver

Uncommon: Temporary rise in liver enzymes.

Skin

Uncommon: Redness.
Rare: Rash, itching, hives.
Not Known: Severe skin reactions, allergic sun sensitivity, purple spots.

Kidneys & Urinary

Uncommon: Frequent urination, painful urination.

Reproductive System

Uncommon: Erectile dysfunction.

General Symptoms

Common: Feeling unwell.
Uncommon: General pain, chills.

Special Warnings

Throat swelling can be life-threatening.
Pregnancy use (as a tocolytic) has reported serious cases.
Dialysis patients with low fluid levels may experience a sharp drop in blood pressure.

Precautions of Nifedipine 20 mg Tablet

Important Precautions for Nifedipine Tablets 20 mg

Not a Beta-Blocker

Nifedipine is not a beta-blocker.
If you’re stopping a beta-blocker, don’t stop suddenly. Reduce the dose slowly over 8–10 days to avoid serious side effects.
Nifedipine won’t protect you from problems caused by stopping other blood pressure medicines suddenly.

Taking with Other Medicines

You can take nifedipine with other blood pressure medicines, including beta-blockers.
But be careful: combining them may cause dizziness or fainting when standing up (called postural hypotension).
Nifedipine won’t stop the “rebound” effect (rise in blood pressure) that can happen after stopping other medicines.

Heart & Blood Pressure Risks

Use nifedipine carefully if you have:

Very low blood pressure (systolic pressure below 90 mmHg)
Heart failure
Severe narrowing of heart valves (aortic stenosis)
Weak heart function (poor cardiac reserve)

Sometimes, nifedipine can make heart failure worse.

Pregnancy & Breastfeeding

Pregnancy: Only use nifedipine if absolutely needed, such as in severe high blood pressure that doesn’t respond to other treatments.
Breastfeeding: Not recommended. Nifedipine can pass into breast milk, and its effects on babies are unknown.
If used with IV magnesium sulfate during pregnancy, blood pressure may drop too much—this can harm both mother and baby. Close monitoring is needed.

Diabetes

If you have diabetes, nifedipine may affect your blood sugar control. Your doctor may need to adjust your treatment.

Liver & Kidney Health

If you have liver problems, your doctor may lower your dose and monitor you closely.
In dialysis patients with high blood pressure and low fluid levels, nifedipine may cause a sharp drop in blood pressure.

Drug Interactions

Some medicines can increase the amount of nifedipine in your body. This may cause your blood pressure to drop too much. Tell your doctor if you take:

Type of Medicine	Examples
Antibiotics	Erythromycin
Antifungals	Ketoconazole
HIV Medicines	Ritonavir
Antidepressants	Fluoxetine, Nefazodone
Others	Valproic acid, cimetidine, and Quinupristin/Dalfopristin

Your doctor may need to adjust your dose or monitor your blood pressure more closely.

Lactose Warning

Nifedipine contains lactose.
Do not take it if you have:
- Galactose intolerance.
- Lapp lactase deficiency.
- Glucose-galactose malabsorption.

Storage instruction of Nifedipine 20 mg Tablet

Store below 30°C.

Keep out of reach of children.

Packing details of Nifedipine 20 mg Tablet

3×10 Alu/PVC Blister

Nifedipine 20 mg Tablet is available in an Alu/PVC blister of 10 tablets. Such 3 blisters in a unit carton with package insert.

interested? let’s talk.

Contact us directly to receive full information on the product, the formulation, the science behind it, stability data, and more. Our Business Development Manager is a click away.

Please enable JavaScript in your browser to complete this form.

Company Name

Layout

Name

Country

Phone

Leave Message