Nifedipine 10 mg Tablet
Nifedipine 10 mg Tablet
Therapeutic Class: Cardiovascular Agents
Dosage Forms: Tablets
Brand Name: Nifedipine 10 mg Tablet™
How it works?
Uses of Nifedipine 10 mg Tablet
Nifedipine is a powerful calcium channel blocker from the 1,4-dihydropyridine class. It works by relaxing blood vessels and improving blood flow, especially to the heart.
Precautions of Nifedipine 10 mg Tablet
Nifedipine 10 mg Tablet Precautions You Should Know
General Safety
- Not a beta-blocker: If you’re stopping a beta-blocker, do it slowly over 8–10 days. Nifedipine won’t protect you from sudden withdrawal effects.
- Can be combined with other blood pressure medicines, but this may cause dizziness or fainting when standing up (postural hypotension).
Heart Health
- Use with caution if you have:
- Weak heart function (poor cardiac reserve)
- Heart failure,it may get worse in some cases
- Very low blood pressure (systolic below 90 mmHg)
- Severe narrowing of the heart valve (aortic stenosis)
- Some people may feel chest pain within a few hours of starting the medicine. If this happens, stop taking it and talk to your doctor.
Blood Pressure Monitoring
- Dialysis patients with high blood pressure and low fluid levels may experience a sharp drop in blood pressure.
- Blood pressure should be closely watched if you’re also taking IV magnesium sulfate, especially during pregnancy.
Pregnancy & Breastfeeding
- Pregnancy: Only use nifedipine if absolutely necessary, such as in severe high blood pressure that doesn’t respond to other treatments.
- Breastfeeding: Not recommended, as the drug can pass into breast milk and its effects on babies are unknown.
Diabetes
- If you have diabetes, your blood sugar control may need adjusting while on nifedipine.
Liver Function
- If you have liver problems, your doctor may need to lower your dose and monitor you more closely.
- Nifedipine hasn’t been fully studied in people with severe liver disease, so extra caution is needed.
Drug Interactions
Nifedipine is broken down by an enzyme called CYP3A4. Some drugs can affect how nifedipine works by increasing its levels in your body. These include:
| Type of Drug | Examples |
| Antibiotics | Erythromycin |
| Antifungals | Ketoconazole, Itraconazole, Fluconazole |
| HIV Medicines | Ritonavir, Indinavir, Nelfinavir, Saquinavir |
| Antidepressants | Fluoxetine, Nefazodone |
| Others | Valproic acid, cimetidine, and Quinupristin/Dalfopristin |
If you’re taking any of these, your blood pressure should be monitored, and your nifedipine dose may need to be lowered.
Dosages administration of Nifedipine 10 mg Tablet
How to Take a Nifedipine 10 mg Tablet?
Tailored Treatment
- Your doctor will adjust the dose based on your condition and how your body responds.
- The dose is usually increased gradually to avoid side effects.
- Nifedipine 10 mg is ideal for fine-tuning the dose, especially in:
- Patients with low body weight
- Those on multiple blood pressure medicines
- People with cerebrovascular disease (e.g., stroke risk)
For Heart Conditions
Chronic Stable Angina (Chest Pain from Effort)
- Start with: 10 mg twice a day (morning & evening) Or 20 mg twice a day
- Max dose: Up to 60 mg per day, increased slowly if needed
- If there is no improvement after 14 days, your doctor may switch you to a different form (capsules)
For High Blood Pressure (Hypertension)
- Start with: 10 mg twice a day Or 20 mg twice a day
- Max dose: Up to 60 mg per day, adjusted gradually
- If you’re taking certain medicines (CYP3A4 inhibitors or inducers), your dose may need to change—or nifedipine may not be suitable
How to Take It
- Swallow tablets whole with a little water
- Do not chew or crush
- Take every 12 hours (e.g., 8 AM and 8 PM)
- Never take doses less than 4 hours apart
- Avoid grapefruit juice—it can affect how the medicine works
- Can be taken with or without food
Special Populations
| Group | Recommendation |
|---|---|
| Children (<18) | Not recommended—safety not established |
| Elderly (>65) | May need lower doses—body processes drug more slowly |
| Liver problems | Dose may need to be reduced and monitored closely |
| Kidney problems | No dose change needed |
Duration of Use
- Your doctor will decide how long you need to take it.
- If you’re on a high dose, it should be reduced gradually before stopping. Nifedipine is a powerful calcium channel blocker from the 1,4-dihydropyridine class. It works by relaxing blood vessels and improving blood flow—especially to the heart.
Side effects of Nifedipine 10 mg Tablet
What are the side effects of the Nifedipine 10 mg tablet?
Frequency Categories
- Common: Happens in 1 to 10 out of every 100 people
- Uncommon: Happens in 1 to 10 out of every 1,000 people
- Rare: Happens in 1 to 10 out of every 10,000 people
- Not Known: Reported after the drug was released, but frequency is unclear
Nervous System
- Common: Headache
- Uncommon: Dizziness, vertigo, migraine, tremors
- Rare: Tingling or numbness
- Not Known: Sleepiness, reduced sensation
Heart & Blood Vessels
- Common: Swelling (especially in legs), widened blood vessels
- Uncommon: Low blood pressure, fainting, fast heartbeat, palpitations
- Not Known: Chest pain (angina)
Blood & Immune System
- Uncommon: Allergic reactions, swelling in throat or face
- Rare: Itchy skin, rash, hives
- Not Known: Serious allergic reactions (anaphylaxis), low white blood cells, high blood sugar
Mental Health
- Uncommon: Anxiety, trouble sleeping
- Not Known: Depression
Eyes
- Uncommon: Blurred or altered vision
- Not Known: Eye pain
Muscles & Joints
- Uncommon: Joint swelling, muscle cramps
- Not Known: Nosebleeds, nasal congestion
Digestive System
- Common: Constipation
- Uncommon: Stomach pain, nausea, indigestion, gas, dry mouth
- Rare: Gum overgrowth
- Not Known: Difficulty swallowing, vomiting, intestinal blockage or ulcers
Liver
- Uncommon: Temporary rise in liver enzymes
Skin
- Uncommon: Redness
- Rare: Rash, itching, hives
- Not Known: Severe skin reactions, allergic sun sensitivity, purple spots
Kidneys & Urinary
- Uncommon: Frequent urination, painful urination
Reproductive System
- Uncommon: Erectile dysfunction
General Symptoms
- Common: Feeling unwell
- Uncommon: General pain, chills
Special Warnings
- Throat swelling can be life-threatening
- Pregnancy use (as a tocolytic) has reported serious cases
- Dialysis patients with low blood volume may experience a sharp drop in blood pressure
Storage instruction of Nifedipine 10 mg Tablet
Store below 30°C.
Keep out of reach of children.
Packing details of Nifedipine 10 mg Tablet
3×10 Alu/PVC Blister
Nifedipine Tablet 10 mg is available in an Alu/PVC blister of 10 tablets. Such 3 blisters in a unit carton with a package insert.
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