Beclomethasone Dipropionate, Ketoconazole & Neomycin Sulphate Cream

Therapeutic Class:

Dosage Forms:

Brand Name: Kozon Cream

How it works?

Beclomethasone Dipropionate, Ketoconazole and Neomycin Sulphate Cream is indicated for the relief of the inflammatory manifestations of corticosteroid responsive dermatoses when complicated by secondary infection caused by organisms sensitive to the components of this dermatologic preparation or when the possibility of such infection is suspected.

Such disorders include: Chronic dermatitis of the extremities, balanoposthitis, eczematoid dermatitis, contact dermatitis, follicular dermatitis, parakeratosis, paronychia, anal pruritus, intertrigo, impetigo, neurodermatitis, angular stomatitis, photosensitivity dermatitis, lichenified inguinal dermatophytosis and tinea infections such as tinea pedis, tinea cruris and tinea corporis.
As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary.

A small quantity of Beclomethasone Dipropionate, Ketoconazole and Neomycin Sulphate Cream should be applied to cover completely the affected area two or three times daily, or as prescribed by the physician. Frequency of application should be determined according to severity of the condition. Duration of therapy should be determined by patient response. In cases of tinea pedis, longer therapy (2 – 4 weeks) may be necessary.

The most frequent adverse reactions reported were burning, irritation, itching and stinging sensation. Less frequent adverse reactions were skin atrophy, cracking and fissuring of the skin, erythema, folliculitis, numbness of fingers, skin atrophy and telangiectasia.
The following additional local adverse reactions have been reported occasionally with topical corticosteroids: dryness, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, striae, and miliaria.
Neomycin occasionally causes skin sensitization. Ototoxicity and nephrotoxicity have been reported with oral administration.

Beclomethasone Dipropionate, Ketoconazole and Neomycin Sulphate Cream is not for ophthalmic use.
Systemic absorption of topical corticosteroids can produce reversible HPA axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal from treatment. Patients applying a topical steroid to a large surface area or to areas under occlusion should be evaluated periodically for evidence of HPA axis suppression.
Manifestations of Cushing syndrome, hyperglycemia, and glucosuria can also be produced in some patients by systemic absorption of topical corticosteroids while on therapy.
Pediatric patients may be more susceptible to systemic toxicity from equivalent doses due to their larger skin surface to body mass ratios.
If irritation or sensitization develops with the use of Kozon Cream, treatment should be discontinued and appropriate therapy instituted.
Prolonged use of topical antibiotics occasionally may result in overgrowth of non-susceptible organisms. If this occurs or if irritation, sensitization or super infection develops, treatment with Kozon Cream should be discontinued and appropriate therapy instituted.

Store below 30 °C preferably in cool and dry place. Protect from light.
Keep the medicine out of reach of children.

Beclomethasone Dipropionate, Ketoconazole and Neomycin Sulphate Cream available in Lami tube with white cap containing 15 g of cream. Such 01 tube in a monocarton with pack insert.

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F. A. Q

Frequently Asked Questions

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We have below MOQ for:

  1. Tablet, Capsules & Softgel: 200000 Units
  2. Ampoules : 100000 Units
  3. Vials: 10000 Units
  4. Ointment and Cream: 15000 Units
  5. Suppository: 50000 Units
  6. Syrup and Liquid: 10000 Units
  7. Sachets : 50000 Units

We do ready the product within 45-60 days after product artwork confirmation from your side. So, including transit time you can get the product within 90 days maximum, either by Air or Sea route.

A product's “shelf life” generally means the length of time you can expect a product to look and act as expected and to stay safe for use. This length of time varies, depending on the type of product, how it is used, and how it is stored.

Our products come with a minimum of 24 months to a maximum of 36 months of shelf life.

For, Primary packaging we use aluminium foil with 20 to 50 micron size and PVC foil with 350 to 400 micron depending on product characteristics and stability.

For, Secondary packing we do use 300 to 400 GSM FFB Card board.

For, Tertiary packing we do us 7 ply 150 GSM corrugated boxes to prevent the damage during transits.

Yes, we do have available for all dossier documents according to GMP guidelines for the respective country. We do also provide COPP and Free sale certificates (FSC) on demand to customers for special import permit type of commercial orders.