What are the uses of Ceftazidime Injection 1gm?
Ceftazidime Injection 1gm inhibits bacterial cell wall synthesis following attachment to penicillin-binding proteins (PBPs). This results in the interruption of cell wall (peptidoglycan) biosynthesis, which leads to bacterial cell lysis and death.
Precautions While Using Ceftazidime Injection 1gm
1. Allergic Reactions (Hypersensitivity)
2. Limited Effectiveness
3. Diarrhoea and Colitis
4. Kidney Health
5. Overgrowth of Other Germs
6. Lab Test Interference
7. Sodium Content
Dosages of Ceftazidime Injection 1gm
Adults and Children Over 40 kg (about 88 lbs)
Given in Separate Doses (Intermittent)
Given All Day Through a Drip (Continuous Infusion)
Children Under 40 kg
Given in Separate Doses
Given All Day Through a Drip
Newborns and Babies Under 2 Months
Giving Ceftazidime Injection 1gm slowly all day (continuous infusion) is not recommended for babies under 2 months.
Older Adults (Over 80 Years)
Liver Problems
For serious liver problems, the doctor will monitor closely.
Kidney Problems
Adults and Children Over 40 kg
| Kidney Function | Dose | How Often |
|---|---|---|
| Mild (50–31 ml/min) | 1 g | Every 12 hours |
| Moderate (30–16 ml/min) | 1 g | Every 24 hours |
| Severe (15–6 ml/min) | 0.5 g | Every 24 hours |
| Very severe (<5 ml/min) | 0.5 g | Every 48 hours |
Start with 1 g as a loading dose. For serious infections, the doctor may increase the dose or give it more often.
Children Under 40 kg
| Kidney Function | Dose (mg/kg) | How Often |
|---|---|---|
| Mild (50–31 ml/min) | 25 | Every 12 hours |
| Moderate (30–16 ml/min) | 25 | Every 24 hours |
| Severe (15–6 ml/min) | 12.5 | Every 24 hours |
| Very severe (<5 ml/min) | 12.5 | Every 48 hours |
Dialysis Patients
Haemodialysis
Peritoneal Dialysis (CAPD)
Haemofiltration (CVVH or CVVHD)
Possible Side Effects of Ceftazidime Injection 1gm
Ceftazidime Injection 1gm may cause side effects in some people. These can range from mild to serious. Below is a summary of known side effects, grouped by how often they happen and which part of the body they affect.
Frequency Guide
Infections
Blood Disorders
Immune System
Nervous System
Veins
Digestive System
Liver
Skin
Kidneys
General Symptoms
Lab Tests
Store below 30°C temperature. Protect from light.
Keep the medicine out of reach of children.
10 ml clear glass vial with a bromobutyl rubber stopper, sealed with a flip-off aluminum seal.
Ceftazidime Injection 1gm in glass vial is supplied with 10 ml plastic ampoule of diluent (Sterilized Water for Injections USP) in unit carton with pack insert
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