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Cefepime and Tazobactam Injection 1125 mg

Cefepime & Tazobactam Injection 1125 mg

Therapeutic Class: Anti-Infectives

Dosage Forms: Injectables

Brand Name: Cefepime & Tazobactam Injection 1125 mg™

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Uses of Cefepime and Tazobactam Injection 1125 mg

What Are The Uses of Cefepime and Tazobactam Injection 1125 mg

This injectable antibiotic combo is prescribed for:

  • Lower respiratory tract infections (e.g., pneumonia, bronchitis)
  • Urinary tract infections (UTIs)
  • Skin and soft tissue infections.
  • Intra-abdominal infections.
  • Gynecological infections.
  • Bloodstream infections (septicemia)
  • Hospital-acquired infections, including ventilator-associated ones.

Precautions of Cefepime and Tazobactam Injection 1125 mg

Safety Precautions & Warnings Cefepime and Tazobactam Injection.

Kidney and Liver Function

  • If someone has kidney or liver problems, extra care is needed when using this medicine.
  • The dose must be adjusted if the patient’s creatinine clearance is less than 60 mL/min (a sign of kidney trouble).
  • This helps prevent medicine buildup in the body, which can be harmful.

Before Starting Treatment

  • Doctors should ask if the patient has ever had an allergic reaction to:
    • Cefepime
    • Other cephalosporins
    • Penicillin or similar antibiotics
    • Any other medications.

Dosages administration of Cefepime and Tazobactam Injection 1125 mg

Cefepime and Tazobactam Injection 1125 mg is best given through IV infusion over 30 minutes but may be used as a deep intramuscular (IM) injection if needed.

Adults:

  • Dosage depends on the severity of infection. Your doctor will determine the right amount and frequency.

Children (2 months to 12 years):

  • Usually given at a dose of 40 to 50 mg per kg of body weight every 8 to 12 hours.
  • The maximum dose should not exceed the recommended adult dose.

Patients with Liver Problems:

  • No dosage changes are needed for those with impaired liver function.
Site and type of infection in adults Dose Frequency Duration (days)
Mild to moderate uncomplicated or complicated UTIs 0.5-1g IV/IM 12 h 7-10
Severe uncomplicated or complicated UTIs 2g IV 12 h 10
Moderate to severe skin and skin structure infection 2g IV 12 h 10
Intra-abdominal infections 2g IV 12 h 7-10

 

Side effects of Cefepime and Tazobactam Injection 1125 mg

Common Side Effects of Cefepime & Tazobactam Injection 1125 mg (Seen in 1% or More Patients)

  • Injection site reactions like
    • Redness or swelling (3.0%)
    • Vein inflammation (phlebitis) (1.3%)
    • Pain or irritation (0.6%)
  • Skin rash (1.1%)

Less Common Side Effects (Seen in 0.1% to 1% Patients)

  • Digestive issues: Diarrhea, nausea, vomiting, colitis (inflammation of the colon)
  • Body reactions: Fever, headache, itching, hives, vaginal infections
  • Mouth yeast infections: Oral moniliasis

Higher doses (2 g every 8 hours) may cause more side effects.

  • Higher rates of:
    • Rash (4%)
    • Diarrhea (3%)
    • Nausea (2%)
    • Vomiting, itching, fever, headache (1% each)

Lab Test Changes (May Not Cause Symptoms)

These are changes seen in blood tests, not always felt by the patient:

More common changes (≥1%):

  • Positive Coombs’ test (16.2%)—indicates immune response, but usually without damage
  • Decrease in phosphorus
  • Increase in liver enzymes (ALT/SGPT, AST/SGOT)
  • More eosinophils (a type of white blood cell)
  • Changes in blood clotting times (PT, PTT)

Less common changes (<1%):

  • Increased: alkaline phosphatase, BUN (kidney function), calcium, creatinine, potassium, and total bilirubin.
  • Decreased: calcium, hematocrit, white blood cells, platelets, and neutrophils.

Storage instruction of Cefepime and Tazobactam Injection 1125 mg

Store below 30°C temperature. Protect from light.

Keep the cefepime and tazobactam injection out of reach of children.

Packing details of Cefepime and Tazobactam Injection 1125 mg

10 ml clear glass vial with bromobutyl rubber stopper, sealed with a flip-off aluminum seal.

Cefepime and Tazobactam Injection 1125 mg in a glass vial is supplied with a 10 ml plastic ampoule of diluent Sterilized Water for Injections USP in a unit carton with a pack insert.

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Top GMP Certified Cefepime and Tazobactam Injection 1125 mg Manufacturer

At Conical Pharmaceuticals, we proudly stand as a trusted manufacturer of Cefepime and Tazobactam Injection 1125 mg  from our GMP certified facility in Ahmedabad, India. Belonging to the cephalosporin antibiotic class, this powerful combination is widely recognized for its role in treating hospital‑acquired infections, urinary tract infections, skin and soft tissue infections, intra‑abdominal infections, and septicemia. Its demand continues to rise as hospitals and healthcare systems seek reliable solutions against multidrug‑resistant bacteria.

As a reliable bulk supplier, we also provide private label contract manufacturing services, supporting large-scale distributors Companies, international importers, hospital procurement teams, pharmaceutical wholesalers, and healthcare, Custom Formulations innovators brands with flexible production and packaging solutions.

Conical Pharmaceuticals actively planning to  exports Cefepime and Tazobactam Injection 1125 mg into Central America (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, Panama), Central Africa (Cameroon, Chad, DRC, Equatorial Guinea, Gabon, Republic of the Congo), and CIS countries (Armenia, Azerbaijan, Belarus, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Uzbekistan). At the same time, we are strengthening distribution in Ethiopia, Kenya, Uganda, Zambia, Iraq, Ghana, Sri Lanka, Nigeria, UAE, Iran, Philippines, Saudi Arabia, Malaysia, and Australia.

Importers benefit from complete regulatory documentation, including GMP Certificate, Free Sale Certificate, COPP, and tailored country‑specific dossiers. MOQ is offered as per buyer requirements, ensuring flexibility for tenders, bulk supply, and private label projects.

CUSTOM PACKAGING

Options available in size and style to meet your exact specifications and branding needs

SAMPLES AVAILABLE

Test before committing to bulk orders with complimentary samples for quality verification

LEAD TIME

45–60 days for timely delivery, ensuring reliable supply chain management

SHELF LIFE

Shelf Life: 24 months.

Frequently Asked Questions

Questions are useful tools, they open lines of communication; give us information; improve interactions, facilitate analysis, and many more.

  • Yes. Conical Pharmaceuticals manufactures and exports Cefepime and Tazobactam Injection 1125 mg from our WHO‑GMP certified facility in Ahmedabad, India. Also, We offer private label and contract manufacturing services, enabling distributors, innovators, and healthcare brands to launch their own products with flexible packaging solutions.

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