Cefazolin Injection 1gm
Cefazolin Injection 1gm (Cefazolin Injection)
Therapeutic Class: Anti-Infectives
Dosage Forms: Injectables
Brand Name: Cefazolin For Injection USP 1000 mg™
How it works?
Uses of Cefazolin Injection 1gm
Uses of Cefazolin Injection 1gm
- Cefazolin is a cephalosporin antibiotic that is given by injection to treat a variety of bacterial infections.
- Doctors often prescribe it for respiratory tract infections, urinary tract infections, skin and soft tissue infections, and bone or joint infections.
- It is also used for biliary tract infections, septicemia, and as surgical prophylaxis to prevent infections after operations.
How It Works
When Cefazolin Injection 1000 mg is given intramuscularly (into a muscle) or intravenously (into a vein), it quickly enters the bloodstream. From there, it travels to the site of infection. Cefazolin works by blocking the bacteria’s ability to build their cell wall, which is essential for survival. Without a proper cell wall, the bacteria die — this is called bactericidal action.
Precautions of Cefazolin Injection 1gm
Cefazolin Injection 1gm should be used carefully in people who are allergic to penicillin.
Some patients have had allergic reactions to both penicillins and cephalosporins, and in rare cases, these reactions can be serious or even life-threatening. Because of this, there is a risk of cross-reactivity between these two types of antibiotics.
If a patient has a known allergy, especially to drugs, cefazolin should only be given when really needed and with extra caution.
If a serious allergic reaction (anaphylaxis) happens, emergency treatment with epinephrine is necessary. Other treatments, such as oxygen, steroids given through a vein, and help with breathing (including intubation), may also be needed.
It is also possible for patients taking cephalosporins like cefazolin to develop a condition called pseudomembranous colitis.
This causes severe diarrhea and should be considered if diarrhea happens while using antibiotics.
Dosages administration of Cefazolin Injection 1gm
Cefazolin Injection 1gm is given intramuscularly or intravenously at the same total daily doses for both routes.
Adults:
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Mild infections: 250–500 mg every 8 hours.
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Acute, uncomplicated UTIs: 1 g every 12 hours (intramuscular only for this frequency).
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Moderate to severe infections: 500 mg–1 g every 6–8 hours.
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Severe infections (e.g., endocarditis): Up to 6 g/day in divided doses.
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Beta-hemolytic streptococcal infections: Continue for at least 10 days.
Renal impairment:
Start with a loading dose, then adjust:
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Creatinine clearance ≤ 0.91 mL/s (≥ 140 µmol/L): 250 mg–1 g every 6–12 hours.
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Creatinine clearance 0.58–0.90 mL/s (141–273 µmol/L): 250 mg–1 g every 8–12 hours.
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Creatinine clearance 0.18–0.57 mL/s (274–406 µmol/L): 125–500 mg every 12 hours.
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Creatinine clearance ≤ 0.17 mL/s (≥407 µmol/L): 125–500 mg every 18 hours.
Surgical prophylaxis:
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Pre-op: 1 g IV/IM 30–60 minutes before surgery.
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During long surgery: 0.5–1 g IV/IM as needed.
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Post-op: 0.5–1 g IV/IM every 6–8 hours for 24 hours (may extend to 3–5 days for high-risk procedures)
Children:
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Mild to moderate infections: 25–50 mg/kg/day in 3–4 divided doses.
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Severe infections: Up to 100 mg/kg/day.
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Not for infants <1 month or premature infants
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Renal impairment: Adjust dose as per guidelines.
Side effects of Cefazolin Injection 1gm
Side effects of Cefazolin Injection 1gm have been reported, including the following:
Gastrointestinal:
Diarrhea, oral thrush, vomiting, nausea, stomach cramps, and loss of appetite may occur. Rarely, symptoms of pseudomembranous colitis can develop.
Allergic:
Infrequent allergic reactions, including anaphylaxis, itching, drug fever, skin rash, and eosinophilia (high eosinophil count).
Hematologic:
Possible effects include neutropenia, anemia, leukopenia, thrombocythemia, and positive Coombs’ tests.
Hepatic and Renal:
Temporary increases in liver enzymes (AST, ALT), BUN, and alkaline phosphatase may be seen, even without signs of organ impairment. Rarely, hepatitis or cholestatic jaundice can occur.
Local Reactions:
Occasional pain or induration at injection sites; phlebitis (vein inflammation) is rare.
Other:
Uncommon reactions include vulvar/genital itching, vaginal infections, and anal itching.
Storage instruction of Cefazolin Injection 1gm
Store below 30°C temperature. Protected from light.
Keep out of reach of children.
Packing details of Cefazolin Injection 1gm
Cefazolin Injection 1gm comes in a clear glass vial that holds 10 mL of medicine. The vial is made of special USP Type III glass for safety and quality. It has a bromobutyl rubber stopper to keep the medicine clean and sealed. The top is covered with a flip-off aluminum seal to protect it until you’re ready to use it.
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Top GMP Certified Cefazolin Injection 1gm Manufacturer
At Conical Pharmaceuticals, we are a trusted manufacturer of Cefazolin Injection 1 gm from our GMP certified facility in Ahmedabad, India. Belonging to the cephalosporin antibiotic class, Cefazolin is widely used for the treatment and prevention of bacterial infections. Its therapeutic applications include respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections, and surgical prophylaxis.
As a reliable bulk injectables supplier, Conical Pharmaceuticals also offers private label contract manufacturing. We support Large scale distributors, International Importers, innovators, and healthcare brands by providing flexible production and packaging solutions tailored to their needs. This approach allows our partners to scale efficiently, meet tender requirements, and introduce products under their own brand identity, backed by full regulatory support and consistent quality.
We are actively planning to exports into Central America (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, Panama), Central Africa (Cameroon, Chad, DRC, Equatorial Guinea, Gabon, Republic of the Congo), and CIS countries (Armenia, Azerbaijan, Belarus, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Uzbekistan), while strengthening distribution in Ethiopia, Kenya, Uganda, Iraq, Ghana, Sri Lanka, Nigeria, UAE, Iran, Philippines, Saudi Arabia, Malaysia, and Australia.
Importers benefit from complete regulatory documentation, including GMP Certificate, Free Sale Certificate, COPP, and tailored country‑specific dossiers to ensure smooth and compliant market entry.
With strong R&D capabilities, Conical Pharmaceuticals delivers consistent quality formulations. MOQ is offered as per buyer requirements, ensuring flexibility for tenders, bulk supply, and private label projects.
CUSTOM PACKAGING
Options available in size and style to meet your exact specifications and branding needs
SAMPLES AVAILABLE
Test before committing to bulk orders with complimentary samples for quality verification
LEAD TIME
45–60 days for timely delivery, ensuring reliable supply chain management
SHELF LIFE
Shelf Life: 24 months under Store in a cool & dry place below 30°C, protected from light and moisture.
Frequently Asked Questions
Questions are useful tools, they open lines of communication; give us information; improve interactions, facilitate analysis, and many more.
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Conical Pharmaceuticals is a premium manufacturer of Cefazolin Injection 1 gm at our GMP certified facility in Ahmedabad, India. We also offer third‑party manufacturing and private label services,
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