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Acetaminophen 500 mg Tablet

Acetaminophen (Paracetamol) 500‑mg-Tablet

Therapeutic Class: Pain Management

Dosage Forms: Tablets

Brand Name: Acetaminophen 500 mg Tablet™

Best Acetaminophen 500 mg Tablet manufacturer, supplier & exporter
Our Certifications
PPB-KENYA
FDA-JORDAN
MOH-GHANA
WHO- GMP
MOH-MYANMAR
NAFDAC NIGERIA

How it works?

Uses of Acetaminophen 500 mg Tablet

  • Headache relief → Effective for tension headaches and migraines.
  • Muscle aches → Provides relief from general body pain and soreness.
  • Back pain → Commonly used for mild to moderate lower back pain.
  • Arthritis pain → Helps reduce minor pain from osteoarthritis and rheumatoid arthritis.
  • Toothache → Provides temporary relief from dental pain.
  • Menstrual cramps → Reduces discomfort during premenstrual and menstrual periods.
  • Cold & flu symptoms → Relieves aches, pains, and fever associated with viral infections.
  • Fever reduction → Lowers elevated body temperature in adults and children over 12 years.

Precautions of Acetaminophen 500 mg Tablet

Important Precautions While Taking Acetaminophen 500 mg Tablet

Avoid Taking Multiple Products

  • Don’t take more than one medicine that contains acetaminophen at the same time.

Risk of Metabolic Acidosis (HAGMA)

  • Rare cases of a serious condition called pyroglutamic acidosis have been reported.
  • This can happen in people with:
    • Kidney problems
    • Sepsis (severe infection)
    • Malnutrition
    • Alcoholism
  • Risk increases if acetaminophen is taken for a long time or with flucloxacillin.
  • If suspected, stop acetaminophen and monitor closely.

Liver & Kidney Health

  • People with liver or kidney disease should talk to a doctor before using acetaminophen.
  • Taking too much can damage the liver—never exceed the recommended dose.

When to See a Doctor

  • If headaches don’t go away
  • If you have mild arthritis and need pain relief daily
  • If symptoms persist or worsen

Glutathione Deficiency

  • Use with caution if you have conditions that lower glutathione (a natural body chemical), such as:
    • Metabolic disorders
    • Malnutrition
    • Chronic illness
  • These conditions may increase the risk of acidosis.

Pregnancy &  Breastfeeding

Pregnancy

  • Studies show no major risks to the baby when acetaminophen is used during pregnancy.
  • Some research on child development is inconclusive.
  • If needed, use the lowest dose for the shortest time.

Breastfeeding

  • Small amounts may pass into breast milk, but not enough to harm the baby.
  • Safe to use while breastfeeding at normal doses.

Dosages administration of Acetaminophen 500 mg Tablet

Dosage Instructions of Acetaminophen 500 mg Tablet

Adults, Elderly & Children (16+ years)

  • Dose: 1–2 tablets
  • Frequency: Up to 4 times daily as needed
  • Maximum: No more than 8 tablets in 24 hours
  • Interval: At least 4 hours between doses

Children (10–15 years)

  • Dose: 1 tablet
  • Frequency: Up to 4 times daily
  • Limit: Do not use for more than 3 days without medical advice.
  • Interval: Minimum 4 hours between doses.

Not Suitable For

  • Children under 10 years of age.

Directions for Use

  • Route: Oral only.
  • Form: Swallow tablets with water.
  • Do not exceed the recommended dose or frequency.

Side effects of Acetaminophen 500 mg Tablet

Side Effects of Acetaminophen 500 mg Tablet

Frequency Classification

  • Very common: ≥1 in 10
  • Common: ≥1 in 100 to <1 in 10
  • Uncommon: ≥1 in 1,000 to <1 in 100
  • Rare: ≥1 in 10,000 to <1 in 1,000
  • Very rare: <1 in 10,000
  • Not known: Cannot be estimated from available data

Blood & Lymphatic Disorders

  • Very rare:
    • Agranulocytosis (low white blood cells)
    • Thrombocytopenia (low platelets)

Immune System Disorders

  • Very rare:
    • Anaphylaxis (severe allergic reaction)
    • Skin rashes, angioedema (swelling)
    • Serious skin reactions (rare cases)

Metabolism & Nutrition Disorders

  • Not known:
    • High anion gap metabolic acidosis (HAGMA), especially in:
      • Sepsis
      • Renal impairment
      • Malnutrition
      • Chronic alcoholism
      • Glutathione deficiency

Respiratory Disorders

  • Very rare:
    • Bronchospasm (more likely in asthmatics sensitive to aspirin/NSAIDs)

Hepatobiliary Disorders

  • Very rare:
    • Hepatic dysfunction (liver damage)

Selected Adverse Reactions Explained

Pyroglutamic Acidosis (HAGMA)

  • May occur due to low glutathione levels
  • Linked to prolonged use or combination with flucloxacillin
  • Recommendation: Discontinue Acetaminophen and monitor closely if suspected

Bronchospasm

  • Rare but possible
  • Higher risk in patients with aspirin-sensitive asthma

Storage instruction of Acetaminophen 500 mg Tablet

Store in a cool, dry place at a temperature below 30°C and away from light.

Keep out of reach of children.

Packing details of Acetaminophen 500 mg Tablet

3×10 Alu/PVC Blister

Acetaminophen 500 mg Tablets is available in an Alu/PVC blister of 10 tablets. Such 03 blisters in a unit carton with a package insert.

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Top GMP Certified Acetaminophen 500 mg Tablet Manufacturer

Conical Pharmaceuticals, headquartered in Ahmedabad, India, is a GMP‑certified manufacturer & exporter of Acetaminophen 500 mg Tablets, delivering premium pharmaceutical and nutraceutical solutions worldwide. These tablets provide effective pain relief and fever reduction, making them suitable for the treatment of headaches, muscle aches, arthritis pain, toothaches, menstrual cramps, back pain, and cold & flu symptoms.

With planned exports to Central Africa, Central America, and the CIS Region, and a strong distribution network across Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, Panama, Cameroon, Chad, DRC, Equatorial Guinea, Gabon, and the Republic of the Congo, we ensure reliable supply and smooth market entry. Expansion into Nigeria, Ghana, Zambia, Zimbabwe, Kenya, the Philippines, Singapore, and Afghanistan further strengthens our global footprint.

Importers benefit from complete regulatory dossier support, including GMP Certification, COA ,COPP and Free Sale Certificates. We also provide third‑party contract manufacturing, private labeling, and custom formulation options, empowering partners to launch their own brands with tailored solutions.

As a trusted contract manufacturer of analgesic and antipyretic tablets, Conical Pharmaceuticals supplies to international importers, large distributors, pharmacy chains, and hospitals. With advanced R&D, flexible MOQ options, and consistent quality assurance, we enable partners to expand their market presence while delivering effective, high‑quality pharmaceutical solutions worldwide.

CUSTOM PACKAGING

Options available in size and style to meet your exact specifications and branding needs

SAMPLES AVAILABLE

Test before committing to bulk orders with complimentary samples for quality verification

LEAD TIME

45–60 days for timely delivery, ensuring reliable supply chain management

SHELF LIFE

Shelf Life: 24 months.

Frequently Asked Questions

Questions are useful tools, they open lines of communication; give us information; improve interactions, facilitate analysis, and many more.

  • Yes, Conical Pharmaceuticals is a GMP‑certified pharma manufacturer in Ahmedabad, India, producing high‑quality analgesic and antipyretic formulations.

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