Cefepime For Injection 1000 mg

Therapeutic Class: Anti-Infectives

Dosage Forms: Injectables

Brand Name: Cefepime For Injection USP 1000 mg

Best Cefepime for Injection 1000 mg manufacturer, supplier & exporter in India.

How it works?

Uses of Cefepime For Injection 1000 mg

What are the uses of  Cefepime For Injection USP 1000 mg

  • Pneumonia and other lung infections.
  • Urinary tract infections (UTIs)
  • Skin and soft tissue infections.
  • Intra-abdominal infections.
  • Severe infections in hospitals, like sepsis or infections caused by Pseudomonas aeruginosa.
  • Febrile neutropenia (infections in patients with low white blood cell counts)

Dosages administration of Cefepime For Injection 1000 mg

Dosages Of Cefepime For Injection 1000 mg

  • Can be administered through a vein (IV) or into a muscle (IM)
  • IV infusion is preferred for serious infections or life-threatening conditions

Treatment Duration

  • Most infections: 7 to 10 days
  • Severe cases or febrile neutropenia: minimum of 7 days, or until neutropenia resolves.
Patient Group Dosage Guidelines
Adults (normal kidney function) Depends on severity; up to 2 g every 8 hours
Elderly (normal kidney function) No dose adjustment needed
Adults with kidney issues Same initial dose; reduce maintenance dose
Dialysis patients Up to 68% removed in dialysis; use 48-hour gap between doses
Children ≤ 40 kg 50 mg/kg every 12 hrs (mild), every 8 hrs (severe), max 10 days
Children 1–2 months old Consider 30 mg/kg every 8–12 hrs; monitor carefully
Children > 40 kg Use adult dosage
Children with kidney issues Adjust dosage similar to renal-impaired adults
Liver impairment patients No dose adjustment required

 

Side effects of Cefepime For Injection 1000 mg

Common Side Effects of Cefepime For Injection 1000 mg

These are usually mild and temporary:

  • Digestive issues: Diarrhea, nausea, vomiting
  • Skin rash
  • Vein reactions at the injection site, such as swelling or pain.
  • Allergy-like symptoms: itching, redness.
  • Low red or white blood cell count, which may cause fatigue or reduced immunity.

Less Common Side Effects

May occur in some patients:

  • Yeast infections, like oral thrush or vaginal infection.
  • Fever or chills.
  • Headaches or dizziness.
  • Digestive tract inflammation (colitis or pseudomembranous colitis)
  • Increased levels in lab tests, such as liver enzymes or kidney markers.
  • Changes in blood clotting times (usually detected by blood tests)

Rare but Serious Side Effects

These require medical attention if they occur:

  • Severe allergic reactions (swelling, difficulty breathing, anaphylaxis)
  • Confusion, hallucinations, or seizures.
  • Kidney damage or failure, especially in people with existing kidney problems.
  • Skin reactions like Stevens-Johnson Syndrome or toxic epidermal damage.
  • Blood disorders, such as a sharp drop in white cells or platelets.
  • Heart and circulation issues, such as abnormal bleeding or vessel swelling.

Children and Infants

  • The side effect profile in children is similar to adults.
  • Care is needed when dosing children with kidney issues.

Precautions of Cefepime For Injection 1000 mg

  • Serious allergic reactions can happen with cefepime, including rare but potentially life-threatening cases.
  • Stop treatment immediately if any signs of allergy (like rash, swelling, or breathing issues) occur.
  • Before starting treatment:
    • Ask the patient if they’ve ever had a strong allergic reaction to cefepime, cephalosporins, penicillins, or any other beta-lactam antibiotics.
    • Use extra caution with patients who’ve had mild allergic reactions to similar drugs.
  • Asthma- or allergy-prone patients need close monitoring—especially with the first dose.
  • In case of a serious reaction, emergency treatment like epinephrine and supportive care may be needed.
  • Always be cautious when giving antibiotics to patients with any history of drug allergies.

Storage instruction of Cefepime For Injection 1000 mg

Store below 30°C temperature. Protect from light.

Keep the medicine out of reach of children.

Packing details of Cefepime For Injection 1000 mg

10 ml clear glass vial with bromobutyl rubber stopper, sealed with a flip-off aluminum seal.

Cefepime for Injection USP 1000 mg or Cefepime for Injection USP 1gm in a glass vial is supplied with a 10 ml plastic ampoule of diluent Sterilized Water for Injections USP in a unit carton with a pack insert.

 

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