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Ceftriaxone & Sulbactam injection is a combination antibiotic injection used to treat a wide range of bacterial infections. Here’s how it works
Stops Bacteria from Constructing Their Cell Walls → Ceftriaxone acts on the building of the bacterial cell wall, weakening bacteria and causing them to burst.
Protects Ceftriaxone from Being Degraded → Sulbactam guards ceftriaxone against certain chemicals (such as beta-lactamase enzymes) that bacteria employ to become resistant to antibiotics.
Ceftriaxone & Sulbactam Injection is used to treat a variety of bacterial infections. It is especially helpful in managing moderate to severe infections, including
Ceftriaxone and Sulbactam Injection Uses.
– Serious Blood Infections.
– Sepsis (a life-threatening body-wide infection)
– Brain & Nervous System.
– Meningitis (inflammation of the membranes around the brain and spinal cord)
– Lungs & Respiratory Tract.
– Pneumonia.
– Other respiratory infections, including ear, nose, and throat infections.
– Urinary and Reproductive Systems.
– Kidney and urinary tract infections.
– Genital infections, including gonorrhea.
– Bones, Joints & Skin.
– Infections of the bones, joints, soft tissue, wounds, and skin.
– Digestive Tract.
– Abdominal infections, including.
– Peritonitis.
– Infections in the biliary (bile ducts) and gastrointestinal tract.
– Immunocompromised Patients.
– Treatment of infections in individuals with weakened immune systems.
– Surgical Protection.
– Used before surgery for perioperative infection prevention.
Safe Dosing of Ceftriaxone & Sulbactam Injection in Adults, Infants, and Neonates.
Adult Dosage (Ceftriaxone & Sulbactam injection)
Dosage for Neonates, Infants, and Children (up to 12 years old)
Ceftriaxone & Sulbactam Injection Side Effects:
How often side effects happen:
– Very common: Happens in 1 out of 10 people or more.
– Common: Between 1 in 100 and 1 in 10 people.
– Uncommon: Between 1 in 1,000 and 1 in 100 people.
– Rare: Between 1 in 10,000 and 1 in 1,000 people.
– Not known: Not enough data to estimate.
Blood-related Effects of Ceftriaxone & Sulbactam Injection
– Common: Increases in certain white blood cells (eosinophilia), low white cells (leukopenia), and low platelets (thrombocytopenia)
– Uncommon: Anemia, issues with clotting.
– Not known: Severe drop in red blood cells (haemolytic anemia), dangerously low white cell count (agranulocytosis)
Immune System
– Not known: Severe allergic responses (like anaphylactic shock), general allergic reactions, and rare reactions such as Jarisch-Herxheimer.
Nervous System
– Uncommon: Headache, dizziness.
– Rare: Brain dysfunction (encephalopathy)
– Not known: Seizures.
Ear and Balance
– Not known: Sensation of spinning or dizziness (vertigo)
Lungs & Breathing
– Rare: Wheezing or shortness of breath (bronchospasm)
Digestive System
– Common: diarrhea, loose stools.
– Uncommon: Nausea, vomiting.
– Not known: Inflammation of the pancreas, mouth sores, and tongue inflammation.
Liver & Gallbladder
– Common: Elevated liver enzymes in blood tests.
– Not known: Gallstones, jaundice in newborns (kernicterus)
Skin & Allergies
– Common: Skin rash.
– Uncommon: Itching.
– Rare: Hives
– Not known: Serious skin reactions like Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, DRESS, and others.
Kidneys & Urinary
– Rare: Blood or sugar in urine.
– Not known: reduced urine output, temporary kidney deposits.
Injection Site & General Reactions
– Uncommon: Vein inflammation, pain at injection site, fever.
– Rare: Swelling, chills.
Lab Tests—May Be Affected
– Uncommon: Increased creatinine (kidney function marker)
– Not known: False positives in:
– Coombs test.
– Galactosemia test.
– Some sugar (glucose) tests.
Cautions and Warnings for Ceftriaxone & Sulbactam 1500 mg Injection
Allergy Alert:
Risk of Serious Diarrhea:
Anemia Risk:
Kidney Function Monitoring:
Blood Clotting Changes:
Gallbladder Effects:
Use With Caution If:
Store below 30°C. Protect from light and moisture. Keep the medicine out of reach of children.
10 ml clear USP type III glass vial with a grey bromobutyl rubber stopper, sealed with a red BP flip-off aluminum seal.
Ceftriaxone 1000 mg & Sulbactam 500 mg (Ceftriaxone & Sulbactam Injection) dry powder for injection in a glass vial is supplied with a 10 ml plastic ampoule of diluent Sterilized Water for Injections BP in a unit carton with a pack insert.
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A pharma CMO is a special kind of an organization, offering contract manufacturing services to pharmaceutical companies for various kinds of drug formulations.
Reduce overall costs and time to market :
Contract manufacturers already have the needed infrastructure and technical staff, so working with a CMO or CDMO can decrease the cost of manufacturing your pharmaceutical products.
Scalability and flexible production capacity :
You can produce what you need when you need it without worrying about excess capacity. Additionally, CMOs understand the importance of quality and compliance, so you don't have to sacrifice safety for scalability.
Save on upgrading and maintaining equipment :
If you have your manufacturing facility, you’ll have to pay to upgrade your equipment as technology advances—which can get expensive. A CMO/CDMO’s only function is to make and distribute products, so part of their core business responsibility is to update their equipment whenever needed and perform maintenance.
Ease supply chain issues :
During the pandemic, there were several instances of supply chain issues, including medicine shortages. CMOs are generally better equipped than startups to handle a supply chain crisis.
Bandwidth to focus on core competencies
When your company resources aren’t directly allocated to manufacturing and distribution, you have more time to focus on other tasks, like marketing your new drug, researching, or working on drug discovery.
We have 7+ manufacturing sites with a minimum of WHO GMP certification and other country-specific approvals like NAFDAC approved, PPK Kenya Approved, TFDA Tanzania Approved, EU-GMP Approved.
We have below manufacturing capacity:
For Tablet, Capsule, and soft gel: up to 1 million units per shift
For Syrup: up to 0.05 Million per shift
For Ampoule and Vial: up to 0.1 million units per shift
For Ointment and Cream: up to 0.1 million units per shift
For Suppository: 0.1 Million units per shift
Contact us directly to receive full information on the product, the formulation, the science behind it, stability data, and more. Our Business Development Manager is a click away.
Conical Pharmaceuticals is a professionally managed and dynamic organization with decades of experience in the pharmaceutical field. With a desire of providing opportunities for a better life, we work very hard to bring quality drugs to our customers. We have instilled a level of trust and confidence amongst our clients by supplying the best quality products.
