Ceftriaxone & Sulbactam injection is a combination antibiotic injection used to treat a wide range of bacterial infections. Here’s how it works
Stops Bacteria from Constructing Their Cell Walls → Ceftriaxone acts on the building of the bacterial cell wall, weakening bacteria and causing them to burst.
Protects Ceftriaxone from Being Degraded → Sulbactam guards ceftriaxone against certain chemicals (such as beta-lactamase enzymes) that bacteria employ to become resistant to antibiotics.
Ceftriaxone & Sulbactam Injection is used to treat a variety of bacterial infections. It is especially helpful in managing moderate to severe infections, including
Ceftriaxone and Sulbactam Injection Uses.
– Serious Blood Infections.
– Sepsis (a life-threatening body-wide infection)
– Brain & Nervous System.
– Meningitis (inflammation of the membranes around the brain and spinal cord)
– Lungs & Respiratory Tract.
– Pneumonia.
– Other respiratory infections, including ear, nose, and throat infections.
– Urinary and Reproductive Systems.
– Kidney and urinary tract infections.
– Genital infections, including gonorrhea.
– Bones, Joints & Skin.
– Infections of the bones, joints, soft tissue, wounds, and skin.
– Digestive Tract.
– Abdominal infections, including.
– Peritonitis.
– Infections in the biliary (bile ducts) and gastrointestinal tract.
– Immunocompromised Patients.
– Treatment of infections in individuals with weakened immune systems.
– Surgical Protection.
– Used before surgery for perioperative infection prevention.
Safe Dosing of Ceftriaxone & Sulbactam Injection in Adults, Infants, and Neonates.
Adult Dosage (Ceftriaxone & Sulbactam injection)
Dosage for Neonates, Infants, and Children (up to 12 years old)
Ceftriaxone & Sulbactam Injection Side Effects:
How often side effects happen:
– Very common: Happens in 1 out of 10 people or more.
– Common: Between 1 in 100 and 1 in 10 people.
– Uncommon: Between 1 in 1,000 and 1 in 100 people.
– Rare: Between 1 in 10,000 and 1 in 1,000 people.
– Not known: Not enough data to estimate.
Blood-related Effects of Ceftriaxone & Sulbactam Injection
– Common: Increases in certain white blood cells (eosinophilia), low white cells (leukopenia), and low platelets (thrombocytopenia)
– Uncommon: Anemia, issues with clotting.
– Not known: Severe drop in red blood cells (haemolytic anemia), dangerously low white cell count (agranulocytosis)
Immune System
– Not known: Severe allergic responses (like anaphylactic shock), general allergic reactions, and rare reactions such as Jarisch-Herxheimer.
Nervous System
– Uncommon: Headache, dizziness.
– Rare: Brain dysfunction (encephalopathy)
– Not known: Seizures.
Ear and Balance
– Not known: Sensation of spinning or dizziness (vertigo)
Lungs & Breathing
– Rare: Wheezing or shortness of breath (bronchospasm)
Digestive System
– Common: diarrhea, loose stools.
– Uncommon: Nausea, vomiting.
– Not known: Inflammation of the pancreas, mouth sores, and tongue inflammation.
Liver & Gallbladder
– Common: Elevated liver enzymes in blood tests.
– Not known: Gallstones, jaundice in newborns (kernicterus)
Skin & Allergies
– Common: Skin rash.
– Uncommon: Itching.
– Rare: Hives
– Not known: Serious skin reactions like Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, DRESS, and others.
Kidneys & Urinary
– Rare: Blood or sugar in urine.
– Not known: reduced urine output, temporary kidney deposits.
Injection Site & General Reactions
– Uncommon: Vein inflammation, pain at injection site, fever.
– Rare: Swelling, chills.
Lab Tests—May Be Affected
– Uncommon: Increased creatinine (kidney function marker)
– Not known: False positives in:
– Coombs test.
– Galactosemia test.
– Some sugar (glucose) tests.
Cautions and Warnings for Ceftriaxone & Sulbactam 1500 mg Injection
Allergy Alert:
Risk of Serious Diarrhea:
Anemia Risk:
Kidney Function Monitoring:
Blood Clotting Changes:
Gallbladder Effects:
Use With Caution If:
Store below 30°C. Protect from light and moisture. Keep the medicine out of reach of children.
10 ml clear USP type III glass vial with a grey bromobutyl rubber stopper, sealed with a red BP flip-off aluminum seal.
Ceftriaxone 1000 mg & Sulbactam 500 mg (Ceftriaxone & Sulbactam Injection) dry powder for injection in a glass vial is supplied with a 10 ml plastic ampoule of diluent Sterilized Water for Injections BP in a unit carton with a pack insert.
Contact us directly to receive full information on the product, the formulation, the science behind it, stability data, and more. Our Business Development Manager is a click away.
