Acetaminophen Suppository
Paracetamol Suppository
Therapeutic Class: Pain Management
Dosage Forms: Suppositiries
Brand Name: Acetaminophen Suppository™
How it works?
Uses of Acetaminophen Suppository
Acetaminophen suppositories (paracetamol) are widely used because they provide effective pain relief and fever reduction, especially when oral intake isn’t possible (such as in children, patients with nausea/vomiting, or those unable to swallow).
Here are the key uses:
- Fever reduction: Helps lower high body temperature by acting on the brain’s temperature-regulating center.
- Headache relief: Commonly used for tension headaches and mild migraines.
- Toothache and dental pain: Provides relief after dental procedures or for severe tooth pain.
- Muscle and joint pain: Useful for back pain, sports injuries, and arthritis discomfort.
- Post-surgical pain: Helps manage mild to moderate pain after minor surgeries.
- Menstrual pain: Offers gentle relief from cramps.
- Cold and flu symptoms: Reduces fever and body aches associated with viral infections.
Precautions of Acetaminophen Suppository
Do Not Mix With Other Pain Medicines
- Don’t use this product with other medications that contain acetaminophen. It can lead to overdose.
Use With Caution in Certain Health Conditions
- Be careful if you have kidney or liver problems.
- People with non-cirrhotic liver disease are at higher risk of liver damage.
Overdose Warning
- Taking more than the recommended dose can cause serious liver damage.
- If liver damage is suspected, your doctor may order liver function tests.
Keep Out of Reach
- Store safely. Children should not have access to this medicine.
Rare But Serious Condition: HAGMA
Some very sick patients may develop a rare condition called pyroglutamic acidosis, which affects the body’s acid balance.
This may happen in people who:
- Have severe kidney problems or sepsis
- Are malnourished or have chronic alcoholism.
- Are treated with acetaminophen for a long time or with acetaminophen + flucloxacillin.
If this condition is suspected:
- Stop acetaminophen immediately.
- Monitor the patient closely.
- A special urine test (5-oxoproline) may help confirm the diagnosis.
Dosages administration of Acetaminophen Suppository
Dosage for Children
The dose depends on your child’s age and weight:
| Age | Weight | Dose |
|---|---|---|
| 6 to 9 years | 20–30 kg | 1 suppository |
| 10 to 12 years | 30–40 kg | 1 to 2 suppositories |
How to Use
- For rectal use only (insert into the bottom).
- You can give a dose up to 4 times in 24 hours.
- Wait at least 4 hours between doses.
- Do not give more than the recommended dose.
- Do not use for more than 3 days unless your doctor says it’s okay.
- Use whole suppositories only—do not break them before use.
Side effects of Acetaminophen Suppository
Possible Side Effects of Acetaminophen Suppository
Most people use this medicine without any problems. But in rare cases, some side effects may happen:
Stomach and Rectal Issues
- Common: Redness or irritation around the rectal area
Allergic Reactions
- Rare: Skin rash, itching, swelling (especially of the face or throat)
- Very rare: Serious skin reactions
Liver Problems
- Rare: Liver damage
- Overdose warning: Taking too much can cause severe liver injury
Blood Changes
- Rare reports: Low platelet count or other blood disorders
- These may not be directly caused by acetaminophen
Storage instruction of Acetaminophen Suppository
Store in a cool, dry place at a temperature below 30°C and away from light.
Keep out of reach of children.
Packing details of Acetaminophen Suppository
1 × 5 Suppositories
Acetaminophen Suppositories 250 mg is available in a PVC/PE blister of 5 suppositories. Such 01 strips in a unit carton with package insert.
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Contact us directly to receive full information on the product, the formulation, the science behind it, stability data, and more. Our Business Development Manager is a click away.
Reliable GMP Certified Acetaminophen Suppository Manufacturer
At Conical Pharmaceuticals, we manufacture and export Acetaminophen (Paracetamol) Suppositories from our GMP certified facility in Ahmedabad, India. As one of the top suppository manufacturers and a trusted paracetamol suppository exporter, we are recognized for our quality and compliance as a GMP certified paracetamol suppository manufacturer. This product belongs to the therapeutic class of analgesics and antipyretics, widely prescribed for effective pain relief and fever reduction in both pediatric and adult patients requiring rectal administration.
We are actively planning to exports into Central America (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, Panama), Central Africa (Cameroon, Chad, DRC, Equatorial Guinea, Gabon, Republic of the Congo), and CIS countries (Armenia, Azerbaijan, Belarus, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Uzbekistan), while strengthening distribution in Kenya and the Philippines.
Importers benefit from complete regulatory documentation, including GMP Certificate, Free Sale Certificate, COPP, and tailored country‑specific documents to ensure smooth and compliant market entry.
With strong R&D capabilities, Conical Pharmaceuticals delivers reliable formulations, serving hospitals, tenders, distributors, and private label partners worldwide.
CUSTOM PACKAGING
Options available in size and style to meet your exact specifications and branding needs
SAMPLES AVAILABLE
Test before committing to bulk orders with complimentary samples for quality verification
LEAD TIME
45–60 days for timely delivery, ensuring reliable supply chain management
SHELF LIFE
Shelf Life: 24 months.
Frequently Asked Questions
Questions are useful tools, they open lines of communication; give us information; improve interactions, facilitate analysis, and many more.
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Conical Pharmaceuticals manufactures Acetaminophen Suppository at its GMP certified facility in Ahmedabad, India. specializing in compliant pharmaceutical and nutraceutical manufacturing. planning to export across Central America, Central Africa, CIS Country.
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