Meropenem Injection 1000 mg
- Meropenem For Injection USP 1000 mg
Therapeutic Class: Anti-Infectives
Dosage Forms: Injectables
Brand Name: Meropenem Injection™
How it works?
Uses of Meropenem Injection 1000 mg
Uses of Meropenem Injection 1000 mg:
Meropenem is used to treat a variety of serious bacterial infections in adults and children aged 3 months and older, including:
- Severe pneumonia, such as community-acquired and hospital-acquired (nosocomial) pneumonia
- Broncho-pulmonary infections in patients with cystic fibrosis
- Complicated urinary tract infections
- Complicated intra-abdominal infections
- Intra- and post-partum infections
- Complicated skin and soft tissue infections
- Acute bacterial meningitis
It can also be used to manage fever in neutropenic patients (those with low white blood cell counts) when a bacterial infection is suspected.
Meropenem is effective in treating bacteremia (bacteria in the blood) that occurs with or is suspected to be associated with the infections listed above.
Precautions of Meropenem Injection 1000 mg
The selection of meropenem to treat an individual patient should take into account the appropriateness of using a carbapenem antibacterial agent based on factors such as severity of the infection, the prevalence of resistance to other suitable antibacterial agents, and the risk of selecting for carbapenem-resistant bacteria.
Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter spp. resistance
Resistance to penems of Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter spp.
Prescribers are advised to take into account the local prevalence of resistance in these bacteria to penems.
Hypersensitivity reactions
As with all beta-lactam antibiotics, serious and occasionally fatal hypersensitivity reactions have been reported. Patients who have a history of hypersensitivity to carbapenems, penicillins or other beta-lactam antibiotics may also be hypersensitive to meropenem. Before initiating therapy with meropenem, careful inquiry should be made concerning previous hypersensitivity reactions to beta-lactam antibiotics. If a severe allergic reaction occurs, the medicinal product should be discontinued and appropriate measures taken.
Antibiotic-associated colitis
Antibiotic-associated colitis and pseudomembranous colitis have been reported with nearly all antibacterial agents, including meropenem, and may range in severity from mild to life-threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhoea during or after the administration of meropenem. Discontinuation of therapy with meropenem and the administration of specific treatment for Clostridium difficile should be considered. Medicinal products that inhibit peristalsis should not be given.
Seizures
Seizures have infrequently been reported during treatment with carbapenems, including meropenem.
Hepatic function monitoring
Hepatic function should be closely monitored during treatment with meropenem due to the risk of hepatic toxicity (hepatic dysfunction with cholestasis and cytolysis). Use in patients with liver disease: patients with pre-existing liver disorders should have liver function monitored during treatment with meropenem. There is no dose adjustment necessary.
Direct antiglobulin test (Coombs test) seroconversion
A positive direct or indirect Coombs test may develop during treatment with meropenem.
Concomitant use with valproic acid/sodium valproate/valpromide
The concomitant use of meropenem and valproic acid/sodium valproate/valpromide is not recommended.
This medicinal product contains 90.2 mg of sodium per 1.0 g dose, which should be taken into consideration by patients on a controlled sodium diet.
Dosages administration of Meropenem Injection 1000 mg
Dosage administration of Meropenem Injection 1000 mg:
- The dose and length of treatment depend on the type and severity of the infection and how the patient responds.
- Adults and adolescents may receive up to 2 grams three times daily.
- Children may be given up to 40 mg/kg three times daily.
Higher doses are often needed for infections caused by less susceptible bacteria (like Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter species) or for very severe infections.
Always follow official guidelines and your healthcare provider’s instructions when using meropenem.
Side effects of Meropenem Injection 1000 mg
Side Effects of Meropenem Injection 1000 mg:
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Common:
- Thrombocythemia (high platelet count)
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Uncommon:
- Eosinophilia (high eosinophil count)
- Thrombocytopenia (low platelet count)
- Leucopenia (low white blood cell count)
- Neutropenia (low neutrophil count)
- Agranulocytosis (severe reduction of white blood cells)
- Haemolytic anaemia
- Headache
- Diarrhea, vomiting, nausea, abdominal pain
- Increased liver enzymes (transaminases, alkaline phosphatase, lactate dehydrogenase)
- Rash, itching (pruritis)
- Urticaria (hives)
- Toxic epidermal necrolysis
- Stevens-Johnson syndrome
- Erythema multiforme
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Unknown frequency:
- Drug Reactions with Eosinophilia and Systemic Symptoms (DRESS Syndrome)
- Inflammation and pain
Storage instruction of Meropenem Injection 1000 mg
Store below in cool and dry place. Protect from light.
Keep the medicine out of reach of children.
Packing details of Meropenem Injection 1000 mg
Meropenem Trihydrate For Injection USP 1000 mg is filled in 20ml USP typr I Amber tubular glass Vial, sealed with bromo butyl rubber stopper and white coloured Aluminium flip off and white coloured Aluminium flip off seal.
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Most Trusted GMP Certified Meropenem Injection 1000 mg Manufacturer
At Conical Pharmaceuticals, we are a trusted manufacturer of Meropenem Injection 1000 mg, produced at our GMP‑certified large‑scale facility in Ahmedabad, India. Alongside this, we manufacture a wide range of antibiotic injections, serving the needs of large‑scale distributors, international importers, private label brands, retail chains, and pharmacies.
Our commitment is to deliver consistent quality and reliable supply to support global healthcare partners.
We are recognized as a global exporter of antibiotic formulations, We are planning to distribute across Central America (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, Panama), Central Africa (Cameroon, Chad, DRC, Equatorial Guinea, Gabon, Republic of the Congo), the CIS countries, and key markets such as Iran, Malaysia, Thailand, and Saudi Arabia.
To ensure smooth import processes, we provide complete documentation including GMP Certificate, Free Sale Certificate, COPP, COA, and tailored dossiers.
We supply Meropenem Injection 1000 mg with a lead time of 45–60 days, offering custom packaging and custom formulations to meet specific buyer requirements. As a bulk supplier, we fulfill hospital, tender, and distributor demand worldwide.
Our strong R&D team guarantees that every formulation is safe, effective, and of the highest quality. In addition, we act as a CDMO partner, offering contract manufacturing and private labeling for both branded and generic requirements, giving our partners confidence in every collaboration.
Secure hospital and tender supply with a 45–60-day lead time.
CUSTOM PACKAGING
Options available in size and style to meet your exact specifications and branding needs
SAMPLES AVAILABLE
Test before committing to bulk orders with complimentary samples for quality verification
LEAD TIME
45–60 days for timely delivery, ensuring reliable supply chain management
SHELF LIFE
Shelf Life: 24 months.
Frequently Asked Questions
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Conical Pharmaceuticals is a trusted bulk and institutional supplier, meeting hospital, tender, and distributor demand worldwide with GMP‑certified production.
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