Labetalol Tablet BP 100 mg

Therapeutic Class:

Dosage Forms:

Brand Name: HYBETOL-100

How it works?

Labetalol Tablets BP 100 mg is a combined alpha and beta-adrenoceptor blocker indicated for:
Hypertension, including hypertension in pregnancy.
Angina pectoris with existing hypertension.

Labetalol Tablets BP 100 mg For oral administration only. Labetalol tablets should be taken with food.

Positive antinuclear antibodies unassociated with disease, Dizziness, tingling sensation in scalp usually transient may occur in a few patients early in treatment, Very rare: Tremor has been reported in the treatment of hypertension of pregnancy, Heart failure, Rare: Bradycardia, Very rare: Heart block, Raised liver function tests, Very rare: Jaundice (both hepatocellular and cholestatic), hepatitis and hepatic necrosis. When mild, hepatotoxicity is usually reversible on withdrawal of the drug, Ejaculatory failure, erectile dysfunction, Drug fever.

There have been reports of skin rashes and/or dry eyes associated with the use of beta-adrenoceptor blocking drugs.
There have been reports of severe hepatocellular injury with Labetalol therapy.
Particular care should be taken when labetalol is used in patients with hepatic impairment.
Particular care is required with patients whose cardiac reserve is poor.
Airway obstructions may be aggravated in patients with chronic obstructive pulmonary disorders. Non-selective beta-blockers, such as Labetalol, should not be used for these patients unless no alternative treatment is available.
Labetalol should only be given with caution to patients with first-degree heart block due to its negative effect on conduction time.
Beta adrenoceptor blocking drugs may increase the number and duration of anginal attacks in patients with Prinzmetal’s angina, due to unopposed alpha-receptor mediated coronary artery vasoconstriction. Non-selective beta-blockers, such as Labetalol, should not be used for these patients.
Patients with a history of psoriasis should only be administered beta adrenoceptor blockers after careful consideration.
There have been reports of increased sensitivity towards allergens and the seriousness of anaphylactic reactions with the use of beta adrenoceptor blocking drugs.
Labetalol modifies the tachycardia of hypoglycaemia and it may prolong the hypoglycaemic response to insulin.
Because of negative inotropic effects, care is required when prescribing a beta-adrenoceptor blocking drug with class 1 antidysrhythmic agents such as disopyramide.
Care is required during parenteral administration of preparations containing adrenaline to patients receiving beta-adrenoceptor blocking drugs, as in rare instances vasoconstriction, hypertension and bradycardia may occur.
Great care should be taken with patients with peripheral circulatory disorders such as Raynaud’s disease or syndrome or intermittent claudication.
In patients with phaeochromocytoma, labetalol may be administered only after adequate alpha-blockade is achieved.
All labelling for Labetalol will carry the following warning:
Do not take this medicine if you have wheezing or asthma.

Store below 30oC. Protect from light and moisture.
Keep out of reach of children.

3 x 10 Alu/Alu blister pack
Hybetol-100 is available in an Alu/Alu blister of 10 tablets. Such 03 blisters in a unit carton with package insert.

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F. A. Q

Frequently Asked Questions

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We have below MOQ for:

  1. Tablet, Capsules & Softgel: 200000 Units
  2. Ampoules : 100000 Units
  3. Vials: 10000 Units
  4. Ointment and Cream: 15000 Units
  5. Suppository: 50000 Units
  6. Syrup and Liquid: 10000 Units
  7. Sachets : 50000 Units

We do ready the product within 45-60 days after product artwork confirmation from your side. So, including transit time you can get the product within 90 days maximum, either by Air or Sea route.

A product's “shelf life” generally means the length of time you can expect a product to look and act as expected and to stay safe for use. This length of time varies, depending on the type of product, how it is used, and how it is stored.

Our products come with a minimum of 24 months to a maximum of 36 months of shelf life.

For, Primary packaging we use aluminium foil with 20 to 50 micron size and PVC foil with 350 to 400 micron depending on product characteristics and stability.

For, Secondary packing we do use 300 to 400 GSM FFB Card board.

For, Tertiary packing we do us 7 ply 150 GSM corrugated boxes to prevent the damage during transits.

Yes, we do have available for all dossier documents according to GMP guidelines for the respective country. We do also provide COPP and Free sale certificates (FSC) on demand to customers for special import permit type of commercial orders.